Top 12 Laboratory Manager Skills to Put on Your Resume

A strong resume for a laboratory manager role blends sharp technical mastery with people-first leadership. It signals command of scientific methods and instruments, plus calm control of teams, timelines, budgets, and quality systems. The result: safer labs, tighter data, faster delivery, fewer surprises.

Laboratory Manager Skills

  1. LIMS (Laboratory Information Management System)
  2. GLP (Good Laboratory Practices)
  3. ISO 17025
  4. SAP
  5. PCR (Polymerase Chain Reaction)
  6. GC-MS (Gas Chromatography-Mass Spectrometry)
  7. HPLC (High-Performance Liquid Chromatography)
  8. ELISA (Enzyme-Linked Immunosorbent Assay)
  9. NMR (Nuclear Magnetic Resonance)
  10. Six Sigma
  11. Lean Management
  12. Project Management

1. LIMS (Laboratory Information Management System)

A Laboratory Information Management System centralizes samples, workflows, instruments, and records so the lab hums instead of sputters. Fewer clicks, cleaner trails, faster answers.

Why It's Important

LIMS underpins data integrity, traceability, and throughput. It reduces human error, supports regulatory compliance, and turns raw activity into reliable metrics for decision-making.

How to Improve LIMS (Laboratory Information Management System) Skills

Push your LIMS from “used” to “essential” with targeted upgrades:

  1. Streamline workflows: Map every step, remove redundancies, automate handoffs, adopt barcoding, and standardize forms.

  2. Integrate instruments: Direct instrument-to-LIMS data capture to kill transcription errors and shorten turnaround time.

  3. Harden security: Role-based access, audit trails, encryption at rest and in transit, plus routine backup testing.

  4. Stay current: Apply patches and new releases after controlled testing; document change control.

  5. Train deeply: Role-specific training, quick-reference guides, sandbox practice, and competency checks.

  6. Customize sensibly: Tailor fields, dashboards, and reports to real lab needs while preserving upgrade paths.

  7. Bake in quality: QC checkpoints, controlled vocabularies, validation rules, and periodic data integrity reviews.

  8. Listen to users: Establish a feedback loop and fix friction points fast.

Iterate. Measure. Improve again. That’s how LIMS becomes the lab’s backbone, not just another system.

How to Display LIMS (Laboratory Information Management System) Skills on Your Resume

How to Display LIMS (Laboratory Information Management System) Skills on Your Resume

2. GLP (Good Laboratory Practices)

GLP is the scaffolding for trustworthy science. It codifies planning, documentation, training, equipment control, and archiving so results stand up to scrutiny.

Why It's Important

GLP safeguards consistency and credibility. It protects the lab from compliance pitfalls, elevates data integrity, and signals reliability to regulators and clients.

How to Improve GLP (Good Laboratory Practices) Skills

Strengthen GLP with practical, durable habits:

  1. Stay current: Review GLP requirements regularly and update SOPs when standards change.

  2. Train relentlessly: Onboarding plus periodic refreshers with documented competency assessments.

  3. Build a resilient QMS: Document control, change control, CAPA, deviation handling, and risk-based thinking.

  4. Audit with purpose: Internal audits on a defined cadence; trend findings and close gaps promptly.

  5. Cultivate integrity: Encourage open reporting of issues, no blame games, and clear escalation paths.

  6. Control equipment: Calibration, maintenance, and verification schedules with traceable records.

  7. Validate computerized systems: Risk-based validation, access controls, and audit trails for all critical software.

GLP thrives when culture and systems move in lockstep. Make that alignment visible and repeatable.

How to Display GLP (Good Laboratory Practices) Skills on Your Resume

How to Display GLP (Good Laboratory Practices) Skills on Your Resume

3. ISO 17025

ISO/IEC 17025 defines what competence looks like in testing and calibration labs—methods, validation, impartiality, metrological traceability, and consistent results.

Why It's Important

It proves your lab can generate valid results, consistently. Trust multiplies, accreditation stays intact, and customers return.

How to Improve ISO 17025 Skills

Drive continual improvement with discipline:

  1. Know the standard: Train the team on clauses, intent, and practical application.

  2. Strengthen the QMS: Risk-based processes, document control, method validation/verification, uncertainty estimation, and traceability.

  3. Run sharp internal audits: Independent, scheduled, and evidence-driven; verify effectiveness of corrective actions.

  4. Proficiency testing: Participate routinely; investigate outliers and embed learnings.

  5. Management reviews: Use data—KPIs, complaints, audit trends—to steer actions, not just file minutes.

  6. Customer feedback: Capture, analyze, and close the loop with documented improvements.

  7. CAPA discipline: Root-cause with rigor, verify fixes, and prevent recurrence.

  8. Keep pace: Track regulatory and industry changes that impact methods or competence requirements.

Make evidence your default language. Accreditation follows.

How to Display ISO 17025 Skills on Your Resume

How to Display ISO 17025 Skills on Your Resume

4. SAP

SAP, as an ERP, ties together inventory, procurement, quality, finance, and maintenance. When aligned with lab operations, it becomes the connective tissue from bench to business.

Why It's Important

Accurate inventory, clean batch genealogy, real-time quality status, and traceable costs. Less scrambling, more clarity.

How to Improve SAP Skills

Get more value from SAP without turning the lab upside down:

  1. Leverage S/4HANA (or optimize your current stack): Real-time analytics, simplified data models, faster closes.

  2. Use Quality Management: In-process checks, nonconformance handling, inspection plans, and certificates of analysis.

  3. Customize with restraint: Configure first, extend only where ROI is clear; preserve upgradeability.

  4. Integrate with LIMS: Seamless master data and results flow to cut errors and duplicate work.

  5. Exploit analytics/BI: Dashboards for inventory turns, release cycle times, deviation trends.

  6. Train by role: Planners, analysts, technicians—each needs focused use-cases and quick guides.

  7. Engage the user community: Collect tips, share templates, and maintain super-user networks.

Make SAP serve the science, not the other way around.

How to Display SAP Skills on Your Resume

How to Display SAP Skills on Your Resume

5. PCR (Polymerase Chain Reaction)

PCR amplifies targeted DNA regions so tiny signals become measurable stories. From diagnostics to research, it’s the workhorse.

Why It's Important

Rapid, specific amplification enables detection, quantification, and confirmation when sample input is scarce or complex.

How to Improve PCR (Polymerase Chain Reaction) Skills

Dial in precision, then push throughput:

  1. Smart primer design: Check specificity, avoid hairpins and dimers, and validate in silico before wet runs.

  2. Template quality matters: Clean extraction, intact nucleic acids, and inhibitor-free prep.

  3. Optimize Mg2+ and additives: Titrate magnesium; use DMSO or betaine for GC-rich targets when needed.

  4. Temperature finesse: Gradient PCR to find the sweet spot for annealing and specificity.

  5. Hot-start enzymes: Reduce nonspecific amplification and primer-dimers.

  6. Rigorous controls: No-template, positive, and extraction controls; include standards for qPCR.

  7. Maintain instruments: Calibrated cyclers, verified block uniformity, and documented service.

For advanced needs, consider digital PCR for absolute quantification and rare variant detection.

How to Display PCR (Polymerase Chain Reaction) Skills on Your Resume

How to Display PCR (Polymerase Chain Reaction) Skills on Your Resume

6. GC-MS (Gas Chromatography-Mass Spectrometry)

GC-MS separates volatile components and identifies them with mass spectral fingerprints. High specificity. High sensitivity. Big confidence.

Why It's Important

From environmental residues to forensic tox and flavor profiling, GC-MS offers precise identification and quantification in complex matrices.

How to Improve GC-MS (Gas Chromatography-Mass Spectrometry) Skills

Lift performance with steady care and sharp methods:

  1. Preventive maintenance: Clean ion sources, check vacuum health, replace consumables before they fail.

  2. Column stewardship: Choose the right phase and dimensions; trim routinely; respect temperature limits.

  3. Sample prep discipline: Reduce matrix effects with cleanup; use SPME or derivatization where appropriate.

  4. Method tuning: Optimize carrier flow, oven ramps, injection parameters, and ionization mode to refine resolution and sensitivity.

  5. Data handling: Standardize integration rules, library matching criteria, and calibration models; validate quantitation ranges.

  6. SOPs and training: Clear procedures for startups, shutdowns, tuning, and troubleshooting.

  7. Quality controls: Internal standards, continuing calibration checks, blanks, spikes, and proficiency testing.

Do the boring things brilliantly—results stay rock solid.

How to Display GC-MS (Gas Chromatography-Mass Spectrometry) Skills on Your Resume

How to Display GC-MS (Gas Chromatography-Mass Spectrometry) Skills on Your Resume

7. HPLC (High-Performance Liquid Chromatography)

HPLC separates and quantifies components in liquids with precision and repeatability, anchoring quality control, stability studies, and method validation.

Why It's Important

Clean peaks, tight RSDs, and robust methods mean regulatory confidence and predictable operations.

How to Improve HPLC (High-Performance Liquid Chromatography) Skills

Tighten control. Then go faster without losing resolution:

  1. Maintenance cadence: Replace seals and check valves on schedule, verify pump performance, and calibrate detectors.

  2. Method optimization: Adjust gradients, temperatures, flow rates, and injection volumes; validate system suitability criteria.

  3. Column care: Use appropriate guard columns, respect pH and solvent limits, and store properly to extend life.

  4. Sample prep: Filtration, dilution, SPE or protein precipitation where needed to protect columns and improve reproducibility.

  5. Data integrity: Controlled sequence templates, audit trails, secure CDS configurations, and verified calculations.

  6. Quality checks: System suitability tests, bracketing standards, and control samples.

  7. Upshift when ready: Consider UHPLC for higher throughput once methods and hardware are compatible.

Methodical tweaks beat wholesale overhauls—measure and move.

How to Display HPLC (High-Performance Liquid Chromatography) Skills on Your Resume

How to Display HPLC (High-Performance Liquid Chromatography) Skills on Your Resume

8. ELISA (Enzyme-Linked Immunosorbent Assay)

ELISA detects and quantifies proteins, antibodies, and hormones using enzyme-linked antibodies and colorimetric or fluorescent readouts. Precise. Scalable. Familiar.

Why It's Important

High sensitivity and specificity make ELISA a staple for diagnostics, release testing, and biomarker screening.

How to Improve ELISA (Enzyme-Linked Immunosorbent Assay) Skills

Control the variables that quietly inflate your CV%:

  1. Antibody rigor: Validate capture and detection pairs for affinity and cross-reactivity; lock lots where possible.

  2. Coating and blocking: Tune buffer composition and pH; choose blockers that minimize background without masking epitopes.

  3. Sample handling: Standardize collection, storage, freeze-thaw limits, and diluent matrices.

  4. Assay conditions: Optimize antibody concentrations, incubation times, and temperatures; use consistent shaking and washing.

  5. Reagent quality: Track expiry, storage conditions, and lot-to-lot checks for substrates and buffers.

  6. Equipment checks: Calibrate pipettes, verify washer performance, and qualify plate readers.

  7. Data analysis: Use appropriate curve fits (e.g., 4PL/5PL), include standards and controls, and define acceptance criteria.

  8. Training: Reinforce technique—pipetting accuracy, wash consistency, and timing precision.

Tidy plates, tight curves, trustworthy results.

How to Display ELISA (Enzyme-Linked Immunosorbent Assay) Skills on Your Resume

How to Display ELISA (Enzyme-Linked Immunosorbent Assay) Skills on Your Resume

9. NMR (Nuclear Magnetic Resonance)

NMR reveals structure, dynamics, and interactions by reading nuclear spins in a magnetic field. Complex mixtures yield to clear spectra with the right setup.

Why It's Important

Unambiguous structure elucidation, purity assessments, and kinetic studies—without derivatization or destruction.

How to Improve NMR (Nuclear Magnetic Resonance) Skills

Clarity starts before you press “acquire”:

  1. Sample prep: Use suitable deuterated solvents, correct concentrations, and clean tubes; filter when needed.

  2. Instrument care: Routine shimming, probe tuning/matching, lock stability checks, and temperature verification.

  3. Parameter optimization: Choose appropriate pulse sequences, relaxation delays, number of scans, and spectral widths.

  4. Advanced experiments: 2D and heteronuclear methods to resolve overlap and confirm connectivity.

  5. Processing discipline: Consistent zero-filling, apodization, baseline correction, and phase adjustment.

  6. Training and SOPs: Clear guidance for acquisition and interpretation, plus reference spectra libraries.

  7. Ask for help when it’s novel: Collaborate with core facilities or experts for unusual nuclei or methods.

Good shims, great spectra. It’s that simple—and that fussy.

How to Display NMR (Nuclear Magnetic Resonance) Skills on Your Resume

How to Display NMR (Nuclear Magnetic Resonance) Skills on Your Resume

10. Six Sigma

Six Sigma is a data-first approach to choke off defects and variability using DMAIC, statistical tools, and relentless improvement.

Why It's Important

In the lab, it trims rework, tightens cycle times, and lifts first-pass yield—without gambling on quality.

How to Improve Six Sigma Skills

Make it visible, practical, and contagious:

  1. Train by belt level: Foundations for everyone; deeper methods for project leads.

  2. Map processes: SIPOC and value-stream maps to see the whole flow and spot waste.

  3. Run DMAIC well: Define tightly, measure with validated metrics, analyze with statistics, improve with pilots, and control with SPC.

  4. Use the right tools: Capability analysis, DOE, root-cause techniques, and control charts.

  5. Project selection: Prioritize by impact and feasibility; celebrate wins and publish results.

  6. Cultural anchors: Daily management boards, visible KPIs, and leadership participation.

Precision isn’t an accident—it’s designed.

How to Display Six Sigma Skills on Your Resume

How to Display Six Sigma Skills on Your Resume

11. Lean Management

Lean strips out waste and friction so scientists can focus on science. Flow improves; queues shrink; errors fade.

Why It's Important

Better throughput with the same people and space. Faster answers, cleaner handoffs, happier teams.

How to Improve Lean Management Skills

Small changes, big ripple:

  1. Process mapping: Visualize current state, then design the future state with fewer handoffs and waits.

  2. 5S the lab: Sort, set in order, shine, standardize, sustain—label everything and keep it that way.

  3. Kaizen rhythm: Frequent, focused improvements driven by the people doing the work.

  4. Visual management: Kanban boards, clear WIP limits, color codes, and status signals.

  5. Hunt down waste: Motion, waiting, overprocessing, defects, inventory, transport, overproduction.

  6. Quality at the source: Error-proofing (poka-yoke), standardized work, and immediate feedback loops.

  7. Empower the team: Training, autonomy, and recognition for improvement ideas.

  8. Lean tech: Use LIMS, e-notebooks, and automation where they remove bottlenecks and rework.

Sustainment is the hard part—make it visible and owned.

How to Display Lean Management Skills on Your Resume

How to Display Lean Management Skills on Your Resume

12. Project Management

Plan, resource, execute, and close—while communicating like a metronome. In labs, that means aligning science with schedules and constraints without breaking quality.

Why It's Important

Deadlines hold. Budgets behave. Scope stays true. Teams collaborate instead of collide.

How to Improve Project Management Skills

Make projects predictable without making them rigid:

  1. Use a tool and use it consistently: Centralize tasks, owners, priorities, and status.

  2. Adopt agile where it fits: Short cycles, fast feedback, visible backlogs—especially for method development and R&D.

  3. Communicate on cadence: Brief standups, clear minutes, decision logs, and stakeholder updates.

  4. Time management: Focus blocks, realistic estimates, and buffer for validation and QC.

  5. Risk first: Identify early, rank by impact/likelihood, assign owners, and track mitigations.

  6. Quality woven in: Stage gates, defined acceptance criteria, and documented changes.

  7. Continuously learn: Post-project reviews with actions that actually get done.

Visibility beats heroics. Build systems that make progress obvious.

How to Display Project Management Skills on Your Resume

How to Display Project Management Skills on Your Resume
Top 12 Laboratory Manager Skills to Put on Your Resume